Test Code LAB1225 Opiates, Serum or Plasma, Quantitative
Additional Codes
Mayo Test ID |
FOPIA |
Performing Laboratory
ARUP LaboratoriesMethod Name
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Reporting Name
Opiates, Serum or Plasma, Quant.Specimen Type
VariesSpecimen Required
Submit only one of the following specimens:
Plasma
Specimen Type: Plasma
Container/Tube: Gray top (potassium oxalate/sodium fluoride), Green top (sodium heparin), Lavender top (EDTA), or pink top (K2EDTA)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Draw blood in a gray top (potassium oxalate/sodium fluoride), green (sodium heparin), lavender (EDTA) or pink (K2EDTA) tube(s). Spin down and send 1 mL of plasma refrigerated in a plastic vial.
Note: Label specimen appropriately (plasma).
Serum
Specimen Type: Serum
Collection Container/Tube: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Draw blood in a plain, red-top tube(s). Spin down and send 1 mL of serum refrigerated in a plastic vial.
Note: Label specimen appropriately (serum).
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Varies | Refrigerated (preferred) | 14 days | |
Ambient | 7 days | ||
Frozen |
Reject Due To
Hemolysis | Mild Reject; Gross Reject |
Lipemia | Mild OK; Gross OK |
Other | Separator tubes, Plasma or Whole blood collected in light blue (sodium citrate), specimens exposed to repeat freeze/thaw cycles. |
Reference Values
Drugs covered: codeine, morphine, 6-acetylmorphine, hydrocodone, hydromorphone, oxycodone, and oxymorphone. All drugs covered and the non-glucuronidated (free) form.
Positive cutoff: 2 ng/mL
For medical purposes only; not valid for forensic use.
Interpretation
Identification of specific drug(s) taken by specimen donor is problematic due to common metabolites, some of which are prescription drugs themselves. The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. All drugs covered are the nonglucuronidated (free) form. The concentration value must be greater than or equal to the cutoff to be reported as positive. A very small amount of an unexpected drug analyte in the presence of a large amount of an expected drug analyte may reflect pharmaceutical impurity. Interpretive questions should be directed to the laboratory.
Day(s) Performed
Monday, Wednesday and Friday
Report Available
3-11 daysTest Classification
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.CPT Code Information
80361, 80365
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
FOPIA | Opiates, Serum or Plasma, Quant. | 8217-2 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
Z4427 | 6-acetylmorphine, S/P, Quant | 12788-6 |
Z4428 | Codeine, S/P, Quant | 3506-3 |
Z4429 | Morphine, S/P, Quant | 3827-3 |
Z4430 | Hydrocodone, S/P, Quant | 3680-6 |
Z4431 | Hydromorphone, S/P, Quant | 3683-0 |
Z4432 | Oxycodone, S/P, Quant | 3893-5 |
Z4433 | Oxymorphone, S/P, Quant | 60467-8 |