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Test Code LAB1202 Hantavirus IgM and IgG, ELISA, Serum

Additional Codes

Mayo Test ID
HANGM


Ordering Guidance


This test can be used as an aid for diagnosis of hantavirus infection in patients with appropriate exposure history.



Additional Testing Requirements


Serologic testing should be performed alongside other diagnostic methods and epidemiologic exposure risk assessment.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL Serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial


Useful For

Aid in the diagnosis of Hantavirus infection

Profile Information

Test ID Reporting Name Available Separately Always Performed
HANTM Hantavirus IgM, S No Yes
HANTG Hantavirus IgG, S No Yes
HANTI Hantavirus IgM/IgG, Interpretation No Yes

Method Name

HANTM, HANTG: Enzyme-Linked Immunosorbent Assay (ELISA)

HANTI: Technical Interpretation

Reporting Name

Hantavirus IgM/IgG, ELISA, S

Specimen Type

Serum

Specimen Minimum Volume

Serum: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 21 days
  Frozen  30 days
  Ambient  7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Heat-inactivated specimen Reject

Reference Values

IgM: Negative

IgG: Negative

 

Reference values apply to all ages.

Interpretation

IgM result

IgG result

Interpretation

Negative

Negative

No antibodies to Hantavirus (Sin Nombre or Andes strains) detected. False-negative results may occur in patients tested too soon following infection or in immunocompromised patients.

Negative

Borderline

Possible detection of IgG against Hantavirus (Sin Nombre or Andes strains, unable to differentiate). Consider repeat testing on a new specimen to confirm.

Negative

Positive

IgG against Hantavirus (Sin Nombre or Andes strains, unable to differentiate) detected. Results suggest prior exposure or infection with Hantavirus.

Borderline

Negative

Possible detection of IgM against Hantavirus (Sin Nombre or Andes strains, unable to differentiate). Consider repeat testing on a new specimen to confirm.

Borderline

Borderline

Possible detection of IgM and IgG against Hantavirus (Sin Nombre or Andes strains, unable to differentiate). Consider repeat testing on a new specimen to confirm.

Borderline

Positive

IgG against Hantavirus (Sin Nombre or Andes strains, unable to differentiate) detected. Possible detection of IgM against Hantavirus (Sin Nombre or Andes strains, unable to differentiate). Consider repeat testing on a new specimen to confirm IgM results.

Positive

Negative

IgM against Hantavirus (Sin Nombre or Andes strains, unable to differentiate) detected. Results suggest recent infection with Hantavirus.

Positive

Borderline

IgM against Hantavirus (Sin Nombre or Andes strains, unable to differentiate) detected. Possible detection of IgG against Hantavirus (Sin Nombre or Andes strains, unable to differentiate). Consider repeat testing on a new specimen to confirm IgG results.

Positive

Positive

IgM and IgG against Hantavirus (Sin Nombre or Andes strains, unable to differentiate) detected. Results suggest recent infection with Hantavirus.

Day(s) Performed

Wednesday, Friday

Report Available

Same day/1 to 5 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86790 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HANGM Hantavirus IgM/IgG, ELISA, S 114479-9

 

Result ID Test Result Name Result LOINC Value
HANTG Hantavirus IgG, S 113095-4
HANTI Hantavirus IgM/IgG, Interpretation 69048-7
HANTM Hantavirus IgM, S 113094-7