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Test Code LAB0263426 Selenium, Serum

Additional Codes

Mayo Test ID
SES

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Monitoring selenium replacement therapy

Method Name

Dynamic Reaction Cell-Inductively Coupled Plasma-Mass Spectrometry (DRC-ICP-MS)

Reporting Name

Selenium, S

Specimen Type

Serum


Specimen Required


Patient Preparation: High concentrations of gadolinium, iodine, and barium are known to interfere with most metal tests. If gadolinium-, iodine, or barium-containing contrast media has been administered, the specimen should not be collected for at least 96 hours.

Supplies:

-Metal Free Specimen Vial (T173)

-Metal Free B-D Tube (No Additive), 6 mL (T184)

Collection Container/Tube: 6-mL Plain, royal blue-top Vacutainer plastic trace element blood collection tube

Submission Container/Tube: 7-mL Metal-free, screw-capped, polypropylene vial

Specimen Volume: 0.8 mL

Collection Instructions:

1. Allow the specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction.

2. Remove the stopper. Carefully pour specimen into a metal-free, polypropylene vial, avoid transferring the cellular components of blood. Do not insert a pipette into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.

3. See Metals Analysis Specimen Collection and Transport for complete instructions.


CentraCare Laboratory Services Note:

Aliquot to Mayo metal-free, screw-capped plastic vial within 4 hours of collection.

Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days METAL FREE
  Ambient  28 days METAL FREE
  Frozen  28 days METAL FREE

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

0-2 months: 45-90 mcg/L

3-6 months: 50-120 mcg/L

7-9 months: 60-120 mcg/L

10-12 months: 70-130 mcg/L

13 months-17 years: 70-150 mcg/L

≥18 years: 110-165 mcg/L

Interpretation

Selenium accumulates in biological tissue. The normal concentration in adult human blood serum is 110 to 165 mcg/L. Optimal selenium concentration is age dependent (see Reference Values); children require less circulating selenium than adults.

 

In the state of selenium deficiency associated with loss of glutathione peroxidase activity, the serum concentration is usually below 40 mcg/L.

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Specimen Retention Time

14 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84255

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SES Selenium, S 5724-0

 

Result ID Test Result Name Result LOINC Value
9765 Selenium, S 5724-0

Forms

If not ordering electronically, complete, print, and send General Request (T239)