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Test Code LAB0248781 Gabapentin, Serum

Additional Codes

Mayo Test ID
GABA

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Monitoring serum gabapentin concentrations

 

Assessing compliance

 

Adjusting dosage in patients

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Gabapentin, S

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST is not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Collect specimen immediately before next scheduled dose.

2. Within 2 hours of collection, centrifuge and aliquot serum into plastic vial.


Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

2.0-20.0 mcg/mL

 

Toxic Range: ≥25.0 mcg/mL

Interpretation

Therapeutic ranges are based on specimens collected immediately before the next dose (ie, trough).

 

Most epileptic patients show a response to the drug when the trough concentration is in the range of 2 to 20 mcg/mL. Therapeutic drug monitoring may be useful due to inter-individual variation in pharmacokinetics and dose-dependent bioavailability; specimens for measurements should be collected before the morning dose since the short half-life may affect the interpretation of the concentration.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 2 days

Specimen Retention Time

2 weeks

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80171

LOINC Code Information

Test ID Test Order Name Order LOINC Value
GABA Gabapentin, S 9738-6

 

Result ID Test Result Name Result LOINC Value
80826 Gabapentin, S 9738-6

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Neurology Specialty Testing Client Test Request (T732)

-Therapeutics Test Request (T831)