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Test Code LAB0234961 Buprenorphine Screen with Reflex, Random, Urine

Additional Codes

 

Mayo Test ID
BUPR

 

Useful For

Screening and confirmation for drug abuse or use of buprenorphine

Profile Information

Test ID Reporting Name Available Separately Always Performed
BUPS Buprenorphine Screen, U Yes Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
BUPM Buprenorphine and Metabolite, U Yes No

Testing Algorithm

Testing begins with a screening assay. If the buprenorphine screen is positive, then the liquid chromatography tandem mass spectrometry confirmation with quantification will be performed at an additional charge.

Method Name

Immunoassay

Reporting Name

Buprenorphine Screen w/Reflex, U

Specimen Type

Urine


Ordering Guidance


For screening buprenorphine alone, order BUPS / Buprenorphine Screen, Random, Urine.

 

For comprehensive opioid screening, order TOSU / Targeted Opioid Screen, Random, Urine.

 

For situations where chain of custody is required, a Chain of Custody Kit (T282) is available. For chain-of-custody testing, order BUPMX / Buprenorphine and Norbuprenorphine, Chain of Custody, Random, Urine.



Additional Testing Requirements


If urine creatinine is required or adulteration of the sample is suspected, the following test should also be ordered, ADULT / Adulterants Survey, Random, Urine.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic vial

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. Submit 5 mL in 1 plastic vial.

3. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.

3. Submitting less than 5 mL will compromise the ability to perform all necessary testing.


Specimen Minimum Volume

2.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

Negative

Screening cutoff concentration:

Buprenorphine: 5 ng/mL

Interpretation

If the screen result is negative, buprenorphine concentrations were not detected.

 

If the screen result is positive, then confirmation by liquid chromatography tandem mass spectrometry will be performed.

 

A positive interpretation will be given if either the buprenorphine result is greater than or equal to 5.0 ng/mL or the norbuprenorphine result is greater than or equal to 2.5 ng/mL.

 

The presence of buprenorphine above 5.0 ng/mL or norbuprenorphine above 2.5 ng/mL is a strong indicator that the patient has used buprenorphine.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 2 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80307

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BUPR Buprenorphine Screen w/Reflex, U 93494-3

 

Result ID Test Result Name Result LOINC Value
63119 Buprenorphine Screen, U 93494-3

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.