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General Information:

Web Links:

Mayo Clinic Laboratories

Test Code LAB0233578 Oxycodone with Metabolite Confirmation, Random, Urine

Additional Codes

 

Mayo Test ID
OXYCU

 

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Detection and quantification of oxycodone, oxymorphone, noroxycodone, and noroxymorphone in urine

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Oxycodone w/metabolite Conf, U

Specimen Type

Urine


Ordering Guidance


For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order OXYCX / Oxycodone with Metabolite Confirmation, Chain of Custody, Random, Urine.

 

Additional drug panels and specific requests are available; call 800-533-1710 or 507-266-5700.



Additional Testing Requirements


If urine creatinine is required or adulteration of the specimen is suspected, the following test should also be ordered, ADULT / Adulterants Survey, Random, Urine.



Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.

3. Submitting less than 1 mL will compromise our ability to perform all necessary testing.


Specimen Minimum Volume

2.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

Gross hemolysis OK
Gross icterus OK

Reference Values

Negative

Positive results are reported with a quantitative result.

 

Cutoff concentrations by liquid chromatography tandem mass spectrometry:

Oxycodone: 25 ng/mL

Noroxycodone: 25 ng/mL

Oxymorphone: 25 ng/mL

Noroxymorphone: 25 ng/mL

Interpretation

This procedure reports the total urine concentration; this is the sum of the unconjugated and conjugated forms of the parent drug.

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Specimen Retention Time

14 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

G0480

80365 (if appropriate for select payers)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OXYCU Oxycodone w/metabolite Conf, U 94304-3

 

Result ID Test Result Name Result LOINC Value
62616 Oxycodone-by LC-MS/MS 16249-5
42010 Noroxycodone-by LC-MS/MS 61425-5
35965 Oxymorphone-by LC-MS/MS 17395-5
42011 Noroxymorphone-by LC-MS/MS 90894-7
36022 Oxycodone Interpretation 69050-3

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.