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HelpTest Code LAB0213157 Cocaine and Metabolite Confirmation, Random, Urine
Additional Codes
| Mayo Test ID |
|---|
| COKEU |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Detecting and confirming drug abuse involving cocaine
This test is not intended for employment-related testing.
Method Name
Gas Chromatography Mass Spectrometry (GC-MS) Confirmation with Quantitation
Reporting Name
Cocaine and metabolite Conf, USpecimen Type
UrineOrdering Guidance
1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order COKEX / Cocaine and Metabolite Confirmation, Chain of Custody, Random, Urine.
2. Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.
3. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Random, Urine.
Specimen Required
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Plastic urine container
Submission Container/Tube: 10-mL urine tube
Specimen Volume: 10 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Additional Information:
1. No specimen substitutions.
2. STAT requests are not accepted for this test.
Specimen Minimum Volume
5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days | ||
| Ambient | 72 hours |
Reject Due To
| All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Reference Values
Negative
Positive results are reported with a quantitative gas chromatography mass spectrometry (GC-MS) result.
Cutoff concentrations:
COCAINE BY GC-MS
<50 ng/mL
BENZOYLECGONINE BY GC-MS
<50 ng/mL
Interpretation
Reports will specifically indicate the presence or absence of cocaine and benzoylecgonine.
The presence of cocaine, or its major metabolite, benzoylecgonine, indicates use within the past 4 days.
Cocaine has a 6-hour half-life, so it will be present in urine for 1 day after last use.
Benzoylecgonine has a half-life of 12 hours, so it will be detected in urine up to 4 days after last use.
There is no correlation between concentration and pharmacologic or toxic effects.
Day(s) Performed
Monday, Wednesday, Thursday, Friday
Report Available
2 to 5 daysSpecimen Retention Time
14 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80353
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| COKEU | Cocaine and metabolite Conf, U | 53747-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 2922 | Cocaine-by GC/MS | 20519-5 |
| 2902 | Benzoylecgonine-by GC/MS | 16226-3 |
| 20671 | Cocaine Interpretation | 69050-3 |
| 28080 | Chain of Custody | 77202-0 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.