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Test Code LAB0208014 Celiac Disease Serology Cascade, Serum

Methodology

EliA

Useful for evaluating patients suspected of having celiac disease, including patients with compatible symptoms, patients with atypical symptoms, and individuals at increased risk .

Test includes IgA, tissue transglutaminase (tTg) IgG antibody,tissue transglutaminase (tTg) IgA antibody, gliadin (deamidated) IgG antibody, and gliadin (deamidated) IgA antibody.

Performing Laboratory

CentraCare Laboratory Services

Specimen Requirements

 

Specimen Type: Serum

Container/Tube:

Preferred:  Serum gel or red top

Specimen Volume: 2.5 mL

 

Specimen Transport Temperature

Refrigerated ( serum removed within 8 hours and testing will be performed in less than 48 hours).

Frozen if testing will not be completed within 48 hours

Reference Values

IGA:

0-3 months: 1-34 mg/dl

>3 months - 1 year: 8-91 mg/dl

>1 year - 12 years: 21-291 mg/dl

>12 years - 60 years: 63-484 mg/dl

>60 years: 101 - 645 mg/dl

 

Gliadin (Deamidated) Antibodies IgG and IA:

Negative:  (<7 U/ml)

Equivocal: (7-10 U/ml)

Positive: (.10 U/ml

 

Tissue Transglutaminase (tTG) Antibody IgG and IgA

Negative:  (<7 U/ml)

Equivocal: (7-10 U/ml)

Positive: (>10 U/ml)

Day(s) Test Set Up

Monday, Wednesday, Friday

Test Classification and CPT Coding

83516 Tissue Transglutaminase IgG

83516 Tissue Transglutaminase IgA

83516  Gliadin Deamidated Antibody IgG

83516  Gliadin Deamidated Antibody IgA

82784  IgA