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HelpTest Code LAB0208014 Celiac Disease Serology Cascade, Serum
Methodology
EliA
Useful for evaluating patients suspected of having celiac disease, including patients with compatible symptoms, patients with atypical symptoms, and individuals at increased risk.
Panel Includes: Immunoglobulin A, tissue transglutaminase (tTg) IgG antibody, tissue transglutaminase (tTg) IgA antibody, gliadin (deamidated) IgG antibody, and gliadin (deamidated) IgA antibody.
Performing Laboratory
CentraCare Laboratory Services
Specimen Requirements
Specimen Type: Serum
Container/Tube: Gold top (SST) & Red top (Serum & No Additive)
Specimen Volume: 2 mL
Specimen Minimum Volume: 0.5 mL
Collection Instructions: Label specimen appropriately (serum).
If collecting using a red top with no gel separator, the serum must be removed within 1 hour of collection.
Specimen Transport Temperature
Refrigerated if testing will be completed within 48 hours.
Frozen and removed from gel if testing will not be completed within 48 hours.
Reference Values
IGA:
0-3 months: 1-34 mg/dL
>3 months - 1 year: 8-91 mg/dL
>1 year - 12 years: 21-291 mg/dL
>12 years - 60 years: 63-484 mg/dL
>60 years: 101 - 645 mg/dL
Gliadin (Deamidated) Antibodies IgG and IgA:
Negative: <7 U/mL
Equivocal: 7-10 U/mL
Positive: 10 U/mL
Tissue Transglutaminase (tTG) Antibody IgG and IgA:
Negative: <7 U/mL
Equivocal: 7-10 U/mL
Positive: >10 U/mL
Day(s) Test Set Up
Monday through Friday
Test Classification and CPT Coding
83516 - Tissue Transglutaminase IgG
83516 - Tissue Transglutaminase IgA
83516 - Gliadin (Deamidated) Antibody IgG
83516 - Gliadin (Deamidated) Antibody IgA
82784 - IgA