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HelpTest Code LAB0206003 Complement, Total, Serum
Additional Codes
| Mayo Test ID |
|---|
| COM |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Detection of individuals with an ongoing immune process
First-tier screening test for congenital complement deficiencies
Method Name
Automated Liposome Lysis Assay
Reporting Name
Complement, Total, SSpecimen Type
Serum RedSpecimen Required
Patient Preparation: Fasting preferred.
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Immediately after specimen collection, place the tube on wet ice.
2. After sample has clotted on wet ice, centrifuge at 4° C and aliquot serum into 5 mL plastic vial.
3. Within 30 minutes of centrifugation, freeze specimen. Sample must be placed on dry ice if not frozen immediately.
Freeze serum within 30 minutes of collection and submit frozen.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
30-75 U/mL
Interpretation
Low levels of total complement (total hemolytic complement) may occur during infections, disease exacerbation in patients with systemic lupus erythematosus, and in patients with immune complex diseases such as glomerulonephritis.
Undetectable levels suggest the possibility of a complement component deficiency. Individual complement component assays are useful to identify the specific deficiency.
Day(s) Performed
Monday through Friday
Report Available
1 to 2 daysSpecimen Retention Time
14 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86162
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| COM | Complement, Total, S | 4532-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| COM | Complement, Total, S | 4532-8 |