Test Code LAB0203067 Lupus Anticoagulant InhibitorProfile, Blood

Methodology

Dilute Russell's ViperVenom

Initial testing includes: Protime (PT), activated partial thromoboplastin time (APTT), and dilute Russell Viper Venon Time (DRVVT).

If PT >12.5 sec, PT mix wil be performed at an additional charge

If aPTT >36.5 seconds, APTT mix will be performed at an additional charge

If DRVVT Test Ratio is <1.2, a Silica Clotting Time Test and Ratio will be performed at an additonal charge.

A DRVVT and Silicia Clotting Time 1:1 Mix is performed when clotting times are prolonged at an additional charge.

A thrombin time and/or Heparin anti-XA assay unfractionated may also be performed to rule out Direct Thrombin Inhibitors or Factor X Inhibitors

CentraCare Laboratory Services

Specimen Type: Whole blood

Container/Tube: Light-blue top (sodium citrate)

Specimen Volume: 2 full 2.7 mL tubes

Collection Instructions:

1. Patient should not be receiving heparin.

2. Invert several times to mix blood.

3. If there is a delay in transport of >24 hours from time of draw, process as follows:

A. Spin down for 10 minutes.

B. Aliquot off the platelet poor plasma.

C. Freeze immediately.

D. Send sample frozen.

Additional Information: If ordering more than 1 special coagulation test, please send 1 tube for each test.

Ambient 24 hours-Whole Blood

Frozen-Platelet Poor Plasma

dRVVT Test Ratio <1.2

Silica Clotting Time Test Ratio <1.16

Wednesday

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