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Test Code LAB0201863 Mitochondrial Antibodies (M2), Serum

Additional Codes

Mayo Test ID
AMA

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Establishing the diagnosis of primary biliary cholangitis

 

This test is not useful for indicating the stage or prognosis of the disease or for monitoring the course of the disease.

Method Name

Enzyme Immunoassay (EIA)

Reporting Name

Mitochondrial Ab, M2, S

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK
Heat-treated specimens Reject

Reference Values

Negative: <0.1 Units

Borderline: 0.1-0.3 Units

Weakly positive: 0.4-0.9 Units

Positive: ≥1.0 Units

Reference values apply to all ages.

Interpretation

A positive result for antimitochondrial antibodies of M2 specificity in the setting of chronic cholestasis after exclusion of other causes of liver disease is highly suggestive of primary biliary cholangitis.

Day(s) Performed

Monday through Saturday

Report Available

2 to 3 days

Specimen Retention Time

14 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86381

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AMA Mitochondrial Ab, M2, S 51715-1

 

Result ID Test Result Name Result LOINC Value
AMA Mitochondrial Ab, M2, S 51715-1

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-General Request (T239)

-Gastroenterology and Hepatology Test Request (T728)