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Test Code LAB0201830 5'-Nucleotidase, Serum

Additional Codes

Mayo Test ID
5NTD


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Useful For

Aiding diagnosis and monitoring of hepatobiliary disease and bile duct obstructions

 

Ruling out bone pathology as the source of elevated serum alkaline phosphatase

Method Name

Coupled Enzyme Kinetic Assay

Reporting Name

5'-Nucleotidase, S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  90 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

<4.6 U/L

 

For International System of Units (SI) conversion for Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html.

Interpretation

An elevation of 5'-nucleotidase (5'NT) activity may be seen in all forms of liver disease, although the highest elevations are seen in intra- or extra-hepatic biliary obstruction.

 

5'-nucelotidase may be more specific for intrahepatic cholestasis than gamma glutamyl transferase.

 

Elevation of 5'NT activity is not associated with skeletal disease. Thus, measurement of 5'NT in serum can be used to differentiate observed elevations of alkaline phosphatase due to skeletal disease vs. hepatobiliary disease.

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Specimen Retention Time

2 weeks

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83915

LOINC Code Information

Test ID Test Order Name Order LOINC Value
5NTD 5'-Nucleotidase, S 1690-7

 

Result ID Test Result Name Result LOINC Value
5NTD 5'-Nucleotidase, S 1690-7