Home
HelpTest Code LAB0002368 Immunofixation with Free Light Chains, Quantitative, Urine
Additional Codes
| Mayo Test ID |
|---|
| FIFLC |
Specimen Required
Container/Tube: Two plastic aliquot tubes
Specimen Volume: 8 mL in 2 plastic aliquot tubes, each containing 4 mL
Collection Instructions:
1. Collect urine for 24 hours (No preservative).
2. Refrigerate specimen during the 24-hour collection.
3. Mix the collection and then aliquot urine (4 mL per aliquot) into two plastic aliquot tubes
4. Collection volume and duration are required.
5. Send refrigerated.
Method Name
Qualitative Immunofixation Electrophoresis/Quantitative Immunoturbidimetry
Reporting Name
Immunofix Free Light Chains, USpecimen Type
UrineSpecimen Minimum Volume
4 mL total, 2 vials each containing 2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 21 days |
| Frozen | 180 days |
Reject Due To
All specimens will be evaluated by the processing and performing laboratories for test suitability.Reference Values
Total Protein: <150 mg/d
Free Urinary Kappa Light Chains: 0.00-32.90 mg/L
Free Urinary Kappa Excretion/Day: Refer to report
Free Urinary Lambda Light Chain: 0.00-3.79 mg/L
Free Urinary Lambda Excretion/Day: Refer to report
IFE Interpretation: By report
Interpretation
Results of urine free light chain testing can be used to monitor disease progression or response to therapy in patients for whom urine electrophoresis is unable to provide reliable Bence Jones protein quantification. The results of urine kappa and lambda free light chain quantitative values may be misleading in specimens with high levels of urinary polyclonal free light chains, and absent Bence Jones protein by immunofixation; therefore, correlation with urine immunofixation is required to identify inconsistent results.
Total urinary protein is determined turbidmetrically by adding the albumin and kappa and/or lambda light chains. This value may not agree with the total protein as determined by chemical methods, which characteristically underestimate urinary light chains.
Undetected antigen excess is a rare event but cannot be excluded. Free light chain results should always be interpreted in conjunction with other clinical and laboratory findings.
Performing Laboratory
ARUP LaboratoriesCPT Code Information
84156
86335
83521 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FIFLC | Immunofix Free Light Chains, U | Not Provided |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z5897 | Hours Collected | 30211-7 |
| Z5898 | Total Volume | 19153-6 |
| Z5899 | Total Protein | 2889-4 |
| Z5901 | Free Urinary Kappa Light Chains | 38176-4 |
| Z5912 | Free Urinary Kappa Excretion/Day | 38177-2 |
| Z5913 | Free Urinary Lambda Light Chain | 38178-0 |
| Z5914 | Free Urinary Lambda Excretion/Day | 38169-9 |
| Z5900 | IFE Interpretation | 49277-7 |
Day(s) Performed
Monday through Sunday