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Test Code LAB0002282 Hepatitis A Virus Total Antibodies, Serum

Additional Codes

Mayo Test ID
HAVTA


Necessary Information


Date of collection is required.



Specimen Required


Patient Preparation: For 24 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg. hair, skin, and nail supplements) containing biotin (Vitamin B7).

Collection Container/Tube: Serum gel (red-top tubes are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Collection Instructions:

1. Centrifuge blood collection tube per manufacturer's instructions (eg, centrifuge and aliquot within 2 hours of collection for BD Vacutainer tubes).

2. Aliquot serum into plastic vial.


Useful For

Detection of recent or previous exposure or immunity to hepatitis A.

 

This test should not be used as a screening or confirmatory test for blood or solid or soft tissue donor specimens.

Special Instructions

Method Name

Electrochemiluminescence Immunoassay (ECLIA)

Reporting Name

Hepatitis A Virus Total Ab, S

Specimen Type

Serum SST

Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum SST Frozen (preferred) 90 days
  Refrigerated  6 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

Unvaccinated: Negative

Vaccinated: Positive

Interpretation

This assay detects the presence of hepatitis A virus (HAV)-specific total antibodies (both anti-HAV IgG and anti-HAV IgM combined). A positive result indicates that the patient had hepatitis A either recently or in the past or immunity to hepatitis A from vaccination. A reactive (positive) result by the Elecsys Anti-HAV II assay does not differentiate between acute or past HAV infection or immunity from vaccination, and it does not necessarily rule out other hepatitis infections.

 

If clinically indicated, specific testing for anti-HAV IgM is necessary to confirm the presence of acute or recent hepatitis A. A positive result for anti-HAV total with a negative anti-HAV IgM result indicates immunity to hepatitis A from either past HAV infection or vaccination against HAV.

 

A negative result indicates the absence of recent or past hepatitis A or a lack of immunity to HAV infection. A non-reactive (negative) test result does not exclude the possibility of early acute infection with HAV.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 3 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86708

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HAVTA Hepatitis A Virus Total Ab, S 13951-9

 

Result ID Test Result Name Result LOINC Value
HAVT Hepatitis A Virus Total Ab, S 13951-9

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

Gastroenterology and Hepatology Test Request (T728)

Infectious Disease Serology Test Request (T916)