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HelpTest Code LAB0002214 Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Serum
Additional Codes
| Mayo Test ID |
| HIBAG |
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection without differentiation between the organisms
Monitor antigen levels following initiation of antifungal treatment
Method Name
Enzyme Immunoassay (EIA)
Reporting Name
Histoplasma/Blastomyces Ag, EIA, SSpecimen Type
SerumSpecimen Minimum Volume
1.2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Heat-inactivated specimen | Reject |
Reference Values
Histoplasma/Blastomyces Antigen Result:
Not Detected
Histoplasma/Blastomyces Antigen Value:
Not Detected
Detected: <1.5 ng/mL
Detected: 1.5-25.0 ng/mL
Detected: >25.0 ng/mL
Reference values apply to all ages.
Interpretation
Not detected: No antigen from Histoplasma or Blastomyces detected. False-negative results may occur depending on extent of disease or site of infection. Repeat testing on a new specimen if clinically indicated.
Detected: Antigen from Histoplasma or Blastomyces (unable to differentiate) was detected, below the limit of quantification (<1.5 ng/mL). Result should be correlated with clinical presentation, exposure history, and other diagnostic procedures, such as culture, serology, histopathology, and radiographic findings to aid in the differentiation between histoplasmosis or blastomycosis.
Detected: Antigen from Histoplasma or Blastomyces (unable to differentiate) detected. Result should be correlated with clinical presentation, exposure history, and other diagnostic procedures, such as culture, serology, histopathology, and radiographic findings, to aid in the differentiation between histoplasmosis and blastomycosis.
Detected: Antigen from Histoplasma or Blastomyces (unable to differentiate) detected, above the limit of quantification (>25.0 ng/mL). Result should be correlated with clinical presentation, exposure history, and other diagnostic procedures, such as culture, serology, histopathology, and radiographic findings, to aid in the differentiation between histoplasmosis or blastomycosis.
Day(s) Performed
Monday through Saturday
Report Available
Same day/1 to 3 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
87449
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HIBAG | Histoplasma/Blastomyces Ag, EIA, S | 101587-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 619492 | Histoplasma/Blastomyces Ag Result | 101588-2 |
| 619493 | Histoplasma/Blastomyces Ag Value | 101589-0 |