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Test Code MBL Mannose-Binding Lectin, Serum

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluation of children and adults with a clinical history of recurrent infections


Results may be useful for genetic counseling and support aggressive management of recurrent infections in patients with reduced levels of mannose-binding lectin

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Mannose-Binding Lectin, S

Specimen Type


Specimen Required


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen 7 days

Reject Due To


Mild reject; Gross reject


Mild OK; Gross reject


Mild OK; Gross OK



Reference Values

≥7.8 ng/mL

This reference range applies only to adults.

See Cautions for further information regarding the reference range and clinical interpretation.


Diminished levels of serum mannose-binding lectin (MBL) are consistent with the diagnosis of MBL deficiency.


Levels <7.8 ng/mL are associated with homozygous or mixed heterozygous mutant forms of MBL or mutations in the MBL promoter gene.

Day(s) and Time(s) Performed

Tuesday, Thursday; 9 a.m.

Analytic Time

1 day

Specimen Retention Time

14 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
MBL Mannose-Binding Lectin, S 30152-3


Result ID Test Result Name Result LOINC Value
MANBL Mannose-Binding Lectin, S 30152-3