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Test Code LAB1282 Babesia species, Molecular Detection, PCR, Blood

Additional Codes

Mayo Test ID
LBAB

Useful For

An initial screening or confirmatory testing method for suspected babesiosis during the acute febrile stage of infection in patients from endemic areas, especially when Giemsa-stained peripheral blood smears do not reveal any organisms or the organism morphology is inconclusive.

Reporting Name

Babesia species, PCR, B

Specimen Type

Whole Blood EDTA


Advisory Information


This is a qualitative assay and the results are reported either as negative or positive for targeted Babesia species DNA.



Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 1 mL


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated 7 days

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross reject

Icterus

NA

Other

Green-top (heparin) tube

Reference Values

Negative

Interpretation

A positive result indicates the presence of Babesia species DNA and is consistent with active or recent infection. While positive results are highly specific indicators of disease, they should be correlated with blood smear microscopy, serological results and clinical findings.

 

A negative result indicates absence of detectable DNA from Babesia species in the specimen, but does not always rule out ongoing babesiosis in a seropositive person, since the parasitemia may be present at a very low level or may be sporadic.

 

Other tests to consider in the evaluation of a patient presenting with an acute febrile illness following tick exposure include serologic tests for Lyme disease (Borrelia burgdorferi), and molecular detection (PCR) for ehrlichiosis/anaplasmosis. For patients who are past the acute stage of infection, serologic tests for these organisms should be ordered prior to PCR testing.

Day(s) and Time(s) Performed

Monday through Saturday; Varies

Analytic Time

Same day/1 day

Specimen Retention Time

1 week

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

87798 x 3

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LBAB Babesia species, PCR, B 88461-9

 

Result ID Test Result Name Result LOINC Value
36114 Babesia microti 88452-8
36115 Babesia duncani 88451-0
36116 Babesia divergens/MO-1 88450-2

Method Name

Real-Time Polymerase Chain Reaction (PCR)/DNA Probe Hybridization

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request Form (T244) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/microbiology_test_request_form.pdf).