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Test Code C5DCU C5-DC Acylcarnitine, Quantitative, Urine

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluation of patients with an abnormal newborn screen showing elevations of C5-DC

 

Diagnosis of glutaric aciduria type 1 deficiency

Method Name

Flow Injection Analysis-Tandem Mass Spectrometry (FIA-MS/MS)

Reporting Name

C5-DC Acylcarnitine, QN, U

Specimen Type

Urine


Necessary Information


Include patient's age, family history, clinical condition (asymptomatic or acute episode), diet, and drug therapy information.

Specimen Required


Patient Preparation: If clinically feasible, discontinue L-carnitine supplementation at least 72 hours before specimen collection.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine collection container

Submission Container/Tube: Plastic, 10-mL urine tube (T068)

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. Freeze specimen immediately.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Frozen (preferred) 7 days
  Refrigerated  24 hours

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

NA

Interpretation

Elevated excretion of C5-DC is a specific biochemical marker of glutaric aciduria type 1 that is elevated in affected patients, apparently even in low excretors or those affected individuals with normal levels of glutaric acid in urine.

Day(s) and Time(s) Performed

Monday, Wednesday, Friday; 8 a.m.

Analytic Time

2 days (not reported on Sunday)

Specimen Retention Time

2 months

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82017

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C5DCU C5-DC Acylcarnitine, QN, U In Process

 

Result ID Test Result Name Result LOINC Value
88831 C5-DC Acylcarnitine, QN, U 54279-5
28126 C5-DC Interpretation 59462-2
34470 Reviewed By 18771-6