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Test Code 0293795 11-nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid (Carboxy-THC) Confirmation, Meconium

Additional Codes

 

Mayo Test ID
THCM

 

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Detection of in utero drug exposure to marijuana (tetrahydrocannabinol) up to 5 months before birth

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Carboxy-THC Confirmation, M

Specimen Type

Meconium


Advisory Information


For chain-of-custody testing, order THCMX / 11-nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid (Carboxy-THC) Confirmation, Chain of Custody, Meconium.



Specimen Required


Supplies: Stool container. Small (Random), 4 oz (T288)

Container/Tube: Stool container (T288)

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.


Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time
Meconium Frozen (preferred) 28 days
  Refrigerated  21 days
  Ambient  14 days

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

Grossly bloody reject, Pink OK; stool, diapers

Reference Values

Negative

Positives are reported with a quantitative LC-MS/MS result.

Cutoff concentrations

Tetrahydrocannabinol carboxylic acid (marijuana metabolite) by LC-MS/MS: 10 ng/g

Interpretation

The presence of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid at 10 ng/g or greater is indicative of in utero drug exposure up to 5 months before birth.

Day(s) and Time(s) Performed

Monday through Sunday; Varies

Analytic Time

2 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80349

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
THCM Carboxy-THC Confirmation, M 69007-3

 

Result ID Test Result Name Result LOINC Value
31863 THC 69007-3
31876 Interpretation 69050-3
31877 Chain of Custody 77202-0