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Test Code 0255406 Bartonella Antibody Panel, IgG and IgM, Serum

Additional Codes

Mayo Test ID
BART

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Diagnosis of Bartonella infection, especially in the context of a cat scratch

Testing Algorithm

Includes Bartonella henselae and Bartonella quintana.

 

See Infective Endocarditis: Diagnostic Testing for Identification of Microbiological Etiology in Special Instructions.

Method Name

Immunofluorescence Assay (IFA)

Reporting Name

Bartonella Ab Panel, IgG and IgM

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL


Specimen Minimum Volume

0.15 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 30 days
  Frozen  30 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

NA

Other

NA

Reference Values

Bartonella henselae

IgG: <1:128

IgM: <1:20

 

Bartonella quintana

IgG: <1:128

IgM: <1:20

Interpretation

A positive immunofluorescence assay (IFA) IgM (titer >1:20) suggests a current infection with either Bartonella henselae or B quintana.

 

A positive IgG (titer >1:128) suggests a current or previous infection. Increases in IgG titers in serial specimens suggest active infection.

 

Normal serum specimens usually have an IgG titer of less than 1:128. However, 5% to 10% of healthy controls exhibit a B henselae and B quintana titer of 1:128. Sera from healthy volunteers rarely show titers of 1:256 or greater. IgM titers in normal serum are typically less than 1:20. IgM titers at 1:20 or greater have not been seen in the normal population.

 

Molecular testing of tissue for Bartonella species nucleic acid is recommended in cases of suspected endocarditis.

Day(s) and Time(s) Performed

Monday through Saturday; 9 a.m.

Analytic Time

Same day/1 day

Specimen Retention Time

14 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86611 x 4

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BART Bartonella Ab Panel, IgG and IgM 90251-0

 

Result ID Test Result Name Result LOINC Value
15659 Bart Henselae IgG 6954-2
15660 Bart Henselae IgM 6955-9
15661 Bart Quintana IgG 44827-4
15662 Bart Quintana IgM 44825-8