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Test Code 0252647 21-Hydroxylase Antibodies, Serum

Additional Codes


Mayo Test ID


Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Investigation of adrenal insufficiency


Aid in the detection of those at risk of developing autoimmune adrenal failure in the future

Method Name

Immunoabsorption Assay

Reporting Name

21-Hydroxylase Ab, S

Specimen Type


Specimen Required

Collection Container/Tube: 

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Specimen Minimum Volume

0.19 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 14 days
  Refrigerated  7 days

Reject Due To


Mild OK; Gross reject


Mild OK; Gross reject


Mild OK; Gross OK



Reference Values

<1 U/mL

Reference values apply to all ages.


Positive results (≥1 U/mL) indicate the presence of adrenal autoantibodies consistent with Addison disease.

Day(s) and Time(s) Performed

Thursday; 2 p.m.

Analytic Time

2 days

Specimen Retention Time

2 weeks

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
OH21 21-Hydroxylase Ab, S In Process


Result ID Test Result Name Result LOINC Value
81970 21-Hydroxylase Ab, S 17781-6