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Test Code 0248781 Gabapentin, Serum

Additional Codes

Mayo Test ID
GABA

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Monitoring serum gabapentin concentrations   Assessing compliance   Adjusting dosage in patients

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Gabapentin, S

Specimen Type

Serum Red


Specimen Required


Container/Tube: Red top

Specimen Volume: 1 mL

Collection Instructions:

1. Draw specimen immediately before next scheduled dose.

2. Spin down within 2 hours of draw.


Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross OK

Other

Serum gel tube or whole blood

Reference Values

2.0-20.0 mcg/mL

 

Toxic Range: ≥25.0 mcg/mL

Interpretation

Therapeutic ranges are based on specimens drawn at trough (ie, immediately before the next dose).

 

Most individuals display optimal response to gabapentin with serum levels of 2 to 20 mcg/mL. Some individuals may respond well outside of this range, or may display toxicity within the therapeutic range; thus, interpretation should include clinical evaluation. Some patients require high doses to achieve response, resulting in concentrations as high as 80 mcg/mL. Dosage reduction should be based on signs of toxicity, not the serum concentration.

Day(s) and Time(s) Performed

Tuesday through Saturday; 12 a.m.,

Saturday; 4 p.m.

Analytic Time

Same day/1 day

Specimen Retention Time

2 weeks

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80171

LOINC Code Information

Test ID Test Order Name Order LOINC Value
GABA Gabapentin, S 9738-6

 

Result ID Test Result Name Result LOINC Value
80826 Gabapentin, S 9738-6

Forms

If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen.