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Test Code 0234413 2,3-Dinor-11Beta-Prostaglandin F2 Alpha, Urine

Additional Codes

 

Mayo Test ID
23BPG

 

Useful For

Screening for mast cell activation disorders including systemic mastocytosis

Testing Algorithm

When this test is performed, urine creatinine will always be performed at no additional charge.

Method Name

23BPG: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

AACT: Enzymatic Colorimetric Assay

Reporting Name

2,3-dinor 11B-Prostaglandin F2a, U

Specimen Type

Urine


Advisory Information


 



Specimen Required


Submit only 1 of the following specimens:

 

Patient Preparation: Patients taking aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) may have decreased concentrations of prostaglandin F2 alpha. If possible, discontinue for 2 weeks or 72 hours, respectively, prior to collecting a specimen.

 

Preferred: 24-hour urine collection

Supplies: Plastic, 5-mL tube (T465)

Specimen Volume: 4 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Refrigerate specimen during collection, and send specimen refrigerated.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.

 

Acceptable: Random collection

Supplies: Plastic, 5-mL tube (T465)

Specimen Volume: 4 mL

Collection Instructions:

1. Collect a random urine specimen. 

2.  Refrigerate specimen during collection. Send specimen refrigerated or frozen;  do not add any preservative.


Specimen Minimum Volume

3 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  8 hours

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

NA

Reference Values

<5,205 pg/mg creatinine

Interpretation

Urinary 2,3-dinor-11beta-prostaglandin F2 alpha (2,3-BPG) values above 3,263 pg/mg creatinine are consistent with, but not necessarily diagnostic of, systemic mastocytosis. Values should be interpreted in the context of clinical presentation and additional mast cell disease markers (serum tryptase, urinary N-methyl histamine, and/or urinary leukotriene E4).

Day(s) and Time(s) Performed

Monday, Thursday; 11 a.m.

Analytic Time

2 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

84150

LOINC Code Information

Test ID Test Order Name Order LOINC Value
23BPG 2,3-dinor 11B-Prostaglandin F2a, U In Process

 

Result ID Test Result Name Result LOINC Value
37931 2,3-dinor 11B-Prostaglandin F2a, U In Process

Urine Preservative Collection Options

Ambient

No

Refrigerated

Preferred

Frozen

Yes

6N HCl

No

50% acetic acid

Yes

Na2CO3

Yes

Toluene

No

6N HNO3

No

Boric acid

Yes

Thymol

No